Scientists generate functional, transplantable B cells from mice

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Scientists generate functional, transplantable B cells from mice

Functional B-1 cells derived from mouse embryonic stem cells are capable of long-term engraftment and secrete natural antibodies after transplantation in mice, researchers report. Scientists are interested in B-1 cells generated from pluripotent stem cells because they could be tested as a therapeutic for a broad range of immunological disorders.

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